防二次性损伤大鼠脊髓打击器的研制

A New Design of Impactor without Repeated Impact for Rat's Spine Cord Injury Models

为建立动物脊髓损伤模型,研制了一种新型大鼠脊髓打击器。该装置采用重物自由落体运动原理,采用激光对焦定点打击、步进电机控制调节高度、精密槽型光电传感器检测时间和速度等技术来实现打击棒的定点、定高、定量、一次性打击等打击功能,并可有效避免打击棒的反跳后造成的二次性损伤。实验表明,打击器具有操作简单、可重复性好、精度高等特点,可用来制作不同的动物脊髓损伤模型。

In order to establish animal standard spinal cord injury model, a new rat＇s spinal cord impactor is developed. The new weight-drop device was based on the adsorption principle of electromagnetic. The impacting height can be accurately adjusted by a step motor. The dropping point could be defined by the focus of two tracts of lasers installed beside the impacting bar. A sophisticated optical electronic sensor serves as a detector for the impacting bar＇s certain displacement from free fall to impact and to rebound. The electromagnet below can attract and hold the rebotmded bar. Experiments show that the impactor can realize one- off, quantitative, precise impact to provide different levels of spinal cord injury in rats, and can effectively avoid repeated injury which was caused by the rebound of the impacting bar, and has been successfully designed with simplicity of operation, good repeatability and high precision.