期刊文献+

基质金属蛋白酶及其抑制物与肿瘤的相关性

下载PDF
导出
摘要 恶性肿瘤的发病率逐年上升,严重威胁人类健康。侵袭转移和无限生长是恶性肿瘤患者死亡的主要原因,肿瘤细胞外基质(extracelluarmatrix,ECM)的降解与新生血管的形成是恶性肿瘤发生发展的前提。
作者 姬蕾 赵勤
出处 《广东医学》 CAS CSCD 北大核心 2012年第21期3342-3344,共3页 Guangdong Medical Journal
  • 相关文献

参考文献25

  • 1VAN WAVEREN C, SUN Y, CHEUNG H S,et al. Oxidativephosphorylation dysfunction modulates expression of extracellularmatrix-remodeling genes and invasion [ J ].Carcinogenesis,2006,27(3): 409-418.
  • 2COHEN M, MEISSER A, BISCHOF P. Melalloproteinases and hu-man placental invasiveness[ J].Placenta, 2006 , 27(8) : 783 -793.
  • 3MASKOS K, BODE W. Structural basis of matrix metalloproteinas-es and tissue inhibitors of metalloproteinases[ J].Mol Biotechnol,2003,25(3) : 241 -266.
  • 4BAKER A H,EDWARDS D R,MURPHY G. Metalloproteinaseinhibitors: biological actions and therapeutic opportunities [ J].JCell Sci, 2002, 115(Pt 19) ; 3719 -3727.
  • 5JO Y, YEON J, KIM H J,et al. Analysis of tissue inhibitor ofmetalloproteinases - 2 effect on pro - matrix metalloproteinase - 2activation by membrane - type 1 matrix metalloproteinase usingbaculovirus/insect - cell expression system [ J ].Biochem J,2000,345(Pt3) : 511 -519.
  • 6BJORNLAND K, FLATMARK K, PETTERSEN S, et al. Matrixmetalloproteinases participate in osteosarcoma invasion[ J].J SurgRes, 2005, 127(2) : 151 -156.
  • 7DANIELE A, ZITO A F, GIANNELLI G, et al. Expression ofmetalloproteinases MMP - 2 and MMP - 9 in sentinel lymph nodeand serum of patients with metastatic and non - metastatic breastcancer[ J].Anticancer Res, 2010,30(9) : 3521 -3527.
  • 8SCHMALFELDT B,PRECHTEL D, HARTING K, et al. Increasedexpression of matrix metalloproteinases (MMP) 一2,MMP - 9,andthe urokinase - type plasminogen activator is associated with pro-gression from benign to advanced ovarian cancer[ J].Clin CancerRes, 2001, 7(8): 2396-2404.
  • 9MEYER E,VOLLMER JY, BOVEY R, et al. Matrix metallopro-teinases 9 and 10 inhibit protein kinase C - potentiated, p53 - me-diated apoptosis[ J].Cancer Res, 2005, 65(10) : 4261 -4272.
  • 10WU E, MARI B P, WANG F,et al. Stromelysin -3 suppressestumor cell apoptosis in a murine model [ J ].J Cell Biochem,2001,82(4); 549 -555.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部