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多发性骨髓瘤分子的生物学研究进展

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摘要 多发性骨髓瘤(MM)是一种异质性较强的疾病,影响患者的预后和对治疗的反应。MM存在多种染色体易位,导致MM细胞信号通路异常,促使疾病发生及发展。研究信号分子在MM发生及发展中的作用,有利于开发MM的靶向治疗药物和对MM的危险分层治疗。笔者就MM分子生物学的研究现状进行综述。
出处 《国际输血及血液学杂志》 CAS 2012年第6期508-510,共3页 International Journal of Blood Transfusion and Hematology
基金 国家自然科学基金(81172252)
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