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补体系统与利妥昔单抗靶向治疗的研究进展 被引量:2

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摘要 利妥昔单抗(即美罗华)是B细胞表面CD20分子单克隆抗体。补体依赖的细胞毒效应、抗体依赖细胞介导的细胞毒效应及直接诱导B淋巴细胞凋亡是利妥昔单抗的主要作用机制。然而,很多患者治疗后产生耐药,这无疑限制了其疗效。笔者就补体系统与美罗华的相互作用进行综述。
出处 《国际输血及血液学杂志》 CAS 2012年第6期555-558,共4页 International Journal of Blood Transfusion and Hematology
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