摘要
抑制肾素-血管紧张素-醛固酮系统(RAAS)药物在心血管疾病的预防和治疗中发挥重要作用。联合应用血管紧张素转化酶抑制药(ACEI)和血管紧张素Ⅱ受体拮抗药(ARB)主要用于蛋白尿、RAAS抑制不完全的心力衰竭。联合应用醛固酮抑制剂和ACEI或ARB可降低心力衰竭患者的死亡率。尚需对联合应用肾素抑制药和其他RAAS抑制药做进一步研究。
The drugs that inhibit rennin-angiotensin-aldosterone system (RAAS) play important roles in the prevention and treatment of cardiovascular diseases. The combination use of angiotensin convering enzyme inhibitors (ACEI) and angiotensin Ⅱ receptor antagonist (ARB) is mainly used in proteinuria and heart failure with incomplete RAAS block. The combination use of ACEI or ARB and aldosterone inhibitor may decrease the mortality of heart failure patients. The studies for combination use of rennin inhibitor and other RAAS inhibitor are still needed.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2012年第11期643-647,共5页
Chinese Journal of New Drugs and Clinical Remedies