腹膜透析与血液透析患者生存质量的对比分析

Comparative Analysis of the Survival Quality Between Peritoneal Dialysis and Hemodialysis Patients

目的:比较和分析慢性血液透析(HD)患者和腹膜透析(PD)患者的生存质量,指导临床科学选择透析方式。方法:选取2010年1月-2012年1月在我院持续进行血液透析和腹膜透析的终末期肾病(ESRD)患者共105例,其中HD组患者78例,PD组患者27例。对两组患者进行包括身体状况和精神心理状况在内的生存质量的全面评价。采用肾脏疾病生存质量简表(KDQOL-SF)对患者总体生活质量进行评估,躯体功能状态评估采用Karnof-sky功能状态评分,精神心理状况采用汉密顿抑郁量表(HAMD)进行评价。结果:HD组患者KDQOL-SF平均指数(46.8±12.8)与PD组患者(59.5±13.4)相比具有显著性差异(P<0.05);Karnofsky功能状态评分两组分别为69.3±3.8和72.1±4.6,差异无统计学意义(P>0.05);HAMD因子分析显示,PD组患者在焦虑/躯体化和绝望感方面较HD组有显著性差异(P<0.05)。结论:HD较PD患者总体生存质量更优,但器官功能状态则无显著性差异。同时,PD患者较HD患者精神心理状况更好。

Objective： To compare and analyze the survival quality between peritoneal dialysis and hemodialysis patients.Methods： A total of 105 cases of end-stage renal disease（ESRD） patients were enrolled in this study,and all the patients received peritoneal dialysis（PD group,n=27） or hemodialysis（HD group,n=78） from January 2010 to January 2012 in our hospital.Mental health and quality of life between the two groups were compared.The Karnofsky function condition index was adopted to assess the body function condition,and HAMD was adopted to evaluate the mental state of these patients.Results： The ESRD severity index was significantly different between HD group and PD group（P0.05）.The karnofsky functional status score was respectively 69.3±3.8 in PD group and 72.1±4.6 in HD group,without statistically significant differences.HAMD factor analysis showed that the PD group patients were better in anxiety,somatization,and despair than in HD group（P0.05）.Conclusion： HD patients with severe renal diseases have higher quality of life than PD patients,although no significant difference was found in body function condition between the two groups.However,PD patients have better mental state than HD patients.