摘要
超声激励微泡所产生的"空化效应"能够介导肿瘤细胞凋亡,实现对特定组织释放药物,以及诱导肿瘤血管的栓塞、抑制肿瘤血管的分化增殖,从而发挥靶向治疗的作用。这一项非侵入性治疗策略开拓了肿瘤治疗的思路,并成为新近超声研究中的热点。现就该策略的研究进展进行简要综述。
Cavitation effect by uhrasound-activated microbubbles can mediate tumor ceils necrosis/apoptosis, achieve drug delivery at specific tissue, induce embolization/obstruction of tumor vessels and restrain differentiation or proliferation of tumor vessels. It may offer a new method in the targeted therapy of tumors .Microbubble stimulated by ultrasound as a non-invasive strategy will exploit a new pathway for tumor treatment, and has become a hot topic recently.The status and development of this strategy was reviewed briefly in this article.
出处
《临床超声医学杂志》
2012年第11期756-758,共3页
Journal of Clinical Ultrasound in Medicine
关键词
超声检查
微泡
肿瘤
化疗
Ultrasonography
Microbubble
Tumor
Chemotherapy