Becker痣24例分析

Analysis of 24 Cases of Becker's Nevus

目的 探讨Becker痣的临床特点、合并症和组织病理表现。方法 回顾性分析24例Becker痣临床和病理资料。结果 24例均为散发病例,发病年龄主要集中在10～20岁(83.33%),发病部位以躯干前部和肩胛部居多(45.83%),典型皮损为较大的单侧分布的多毛的色素沉着斑,组织病理主要表现是表皮不同程度角化过度和棘层肥厚,表皮突较规则地向下延伸,基底层黑素颗粒增多,真皮网状层常见较大的形态不规则的平滑肌纤维束,伴有并发症共5例(20.83%)。结论 根据Becker痣典型皮损特点结合组织病理表现临床可以确诊,但是做为一种遗传相关的错构瘤可伴发其他皮肤肌肉骨骼异常,需仔细探明。

Objective To survey the Clinical features, complications and pathological manifestations of Becker＇ s ne- vus. Methods The clinical and pathological materials of 24 cases of Becker＇ s nevus were analysed retro- spectively. Results All of 24 cases occurred sporadically. The age of onset was mainly around I0 -20 years old （83.33%）. The lesions were located predominantly on the anterior trunk or on the scapular region （45.83%）. The typical primary lesion was large, unilateral hyperpigmented patch with hypertrichosis. The histopathology showed varying degrees of h3~perkeratosis and acanthosis of the epidermis, regular elongation of the rete ridges, and basal layer hyperpigmentation , usually larger sized and irregularly formed smooth muscle fiber scattered haphazardly in reticular dermis. Five cases were associated with different kinds of complica- tion （20.83%）. Conclusion Becker＇ s nevus can be confirmed on the basis of clinical features and patho＇- logical examination. As a genetic-related hamartoma, however, Beeker＇ s nevus may be accompanied with other cutaneous and musculoskeletal anomalies that need to be carefully proven.