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肌钙蛋白Ⅰ、血浆脑钠肽对急性心肌梗死危险分层及近期预后价值探讨 被引量:6

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摘要 目的探讨肌钙蛋白Ⅰ(cTnⅠ)、血浆脑钠肽(BNP)水平对急性心肌梗死(AMI)患者冠状动脉病变严重程度和近期预后价值的影响。方法入选162例发病6h内AMI患者,并取80例稳定型心绞痛(SAP)患者作为对照组。所有患者于入院后即刻及入院后24h抽肘前静脉血2次,分别行cTnⅠ、BNP检测,取两次结果的最高值,入院期间均完成冠状动脉造影,随访30d并记录其主要心血管不良事件(MACE)。结果 AMI组与SAP组cTnⅠ、BNP水平比较差异有统计学意义(P<0.01);冠状动脉病变程度越严重,其cTnⅠ、BNP水平越高。冠脉三支病变组的cTnⅠ、BNP显著高于双支病变组及单支病变组,冠脉双支病变组的cTnⅠ、BNP显著高于单支病变组,组间比较有统计学意义(P<0.05)。AMI组中发生MACE各组的cTnⅠ、BNP显著高于无症状者。结论 AMI患者中,cTnⅠ、BNP水平的高低对预测冠状动脉病变的严重程度及近期预后有重要价值。
作者 张萍 宋志宙
出处 《中西医结合心脑血管病杂志》 2012年第11期1298-1299,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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参考文献12

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