泛黄河三角洲地区常见致病菌耐药性的临床研究

Analysis on the resistance mechanism of common pathogens in the Pan-yellow river delta region

目的通过对泛黄河三角洲地区常见致病菌耐药性的临床研究,以期指导因病施治,合理应用抗菌药物,积极减少细菌耐药性的产生。方法采用回顾性调查的方法对2011年1月～12月于本院患者标本所分离的各种病原菌进行药敏试验分析。结果临床分离菌株共5930株,其中革兰阴性菌3760株,占63.41%;革兰阳性菌1872株,占31.57%;真菌298株,占5.02%。结论该地区常见致病菌分离数普遍低于其他地区,药敏试验结果显示细菌的耐药性与其他地区基本持平。

Objective To investigate the rational use of antimicrobial drugs and actively reduce the occurrence of bacterial resistance through the clinical research on resistance of common pathogens in the Pan yellow river delta region. Methods Bacteria susceptiblility testing in hospitalized patients from January to December 2011 were analyzed, retrospectively. Results Total of 5930 clinical isolates were enrolled, 3760 （63.41%） of which were Gram-negative, 1872 （31.57%） of Gram-positive, 298 （5.02%） fungi. Conclusions The common pathogens isolation the region are generally lower than in other regions,but susceptibility testing results show that bacterial resistance is basically the same as other regions.