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急性颅脑损伤外周静脉血白细胞水平变化与SIRS发生的相关分析 被引量:5

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摘要 目的:通过对72例急性颅脑损伤患者外周静脉血白细胞计数及相关生理性指标的测定,来探讨急性颅脑损伤病情严重程度与全身性炎症反应综合征(systemic inflammatory response syndrome,SIRS)发生的关系及预警价值。方法:选择72例中、重型以颅脑损伤为主的患者,分为A组(重型颅脑损伤组)27例,GCS评分3~5分;B组(颅脑损伤合并多发伤)24例,GCS评分3~8分;C组(中型颅脑损伤)21例,GCS评分6~8分;分别于伤后2h、12h、24h、3d用免疫细胞学法检测外周静脉血白细胞水平及相关生理性指标的变化情况,判断SIRS的发生、发展。结果:各组在伤后2h外周静脉血白细胞水平均明显增高(P〈0.01),12~24h白细胞水平达到高峰,1~3d维持在较高水平,无明显增高或下降趋势(P〉0.05)。结论:伤后2h外周静脉血白细胞水平的增加与病情严重程度、SIRS的发生及合并器官损伤的个数和是否伴有失血性休克呈正相关(P〈0.01),且死亡的峰值增加。
出处 《中国医学创新》 CAS 2012年第31期27-28,共2页 Medical Innovation of China
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