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松弛素与肾脏疾病

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摘要 肾脏纤维化是各种肾脏疾病进展到慢性肾衰竭的共同途径和主要病理基础。松弛素是目前新发现的具有抗纤维化效应的激素，它是内源性肾脏保护因子，可通过抑制胶原合成、增加胶原降解延缓肾脏纤维化进程，同时给予外源性重组松弛素可以逆转已形成的纤维化症。此外松弛素还有扩张肾脏血管、增加器官血供、改善凝血状态等作用。
作者 刘小青(综述) 傅睿(审校)
机构地区 南昌江西省儿童医院肾内科
出处 《国际泌尿系统杂志》 2012年第6期840-843,共4页 International Journal of Urology and Nephrology
基金 江西省科技攻关计划
关键词 肾疾病 细胞松驰素类
分类号 R692 [医药卫生—泌尿科学]
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参考文献30

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二级参考文献8

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国际泌尿系统杂志
2012年 第6期

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