急性白血病合并颅内出血的原因分析及防治策略

Factors and Preventing Strategies of Acute Leukemia Complicated with Intracranial Hemorrhage

目的:探讨急性白血病颅内出血的高危因素及防治措施。方法:回顾性分析2006年1月-2011年12月收治的325例急性白血病患者的资料,其中合并颅内出血50例,对其高危因素进行分析。结果:急性白血病颅内出血与白血病颅内浸润、白血病的类型、疾病病程、高白细胞血症、严重的血小板减少、感染相关。结论:颅内出血是导致急性白血病死亡的主要原因,白血病颅内浸润、疾病病程、白血病类型是急性白血病颅内出血发生的主要高危因素。临床上应积极预防,早期诊断,并针对引起颅内出血的高危因素采取积极的措施。

Objective ： To study high risk factors of intracranial hemorrhage of acute leukemia（AL） and to discuss prevention and control measures of intraeranial hemorrhage. Methods ： To review clinical data of 325 patients during from Jan 2006 to Dec 2011 in our hospital, which comhined with intracranial hemorrhage in 50 cases.Results ： The causes of intracranial hemorrhage of acute leukemia were intracranial infiltration of leukemia, the type of leukemia, the disease course, leukocyte hyperlipidemia, thrombocytopenia, fever.Conclusion ： Intraeranial hemorrhage is the main cause of death of AL, intracranial infiltration of leukemia, course of disease, leukemia type AL of the main risk factors of intraeranial hemorrhage.So, clinical doctors should take active prevention, early diagnosis, and take positive measures in the light of the cause of intracranial hemorrhage risk factors.