摘要
目的:观察β受体阻断药(βB)与血管紧张素转换酶抑制药(ACEI)联合治疗慢性心力衰竭的疗效。方法:选择2009年2月-2010年2月康达医院收治的慢性心力衰竭患者102例,随机分为治疗组和对照组。两组均在给予利尿药和强心苷类药的基础上,使用ACEI,治疗组再联合加用βB。治疗6个月后,观察两组状况。结果:治疗组心功能改善总有效率90.38%,对照组72.00%,两组比较差异有统计学意义(P<0.05);治疗组治疗后较治疗前LVESD、LVEDD减少,6min步行试验运动耐量提高,与对照组比较,差异有统计学意义(P<0.05)。结论:在常规抗心衰治疗的基础上联合使用ACEI与βB可获得更好的协同疗效。
Objective:To observe the therapeutic effect of the combined treatment of βB and ACEI.Methods:To randomly divide 102 patients into treatment group and control group.Both groups are given diuretic,cardiac glycoside and ACEI;the treatment group are given βB besides the above-mentioned medicines:the conditions of the groups are compared with each other after 6 months of treatment.Results:The total effective rate of the improvement of heart function in the treatment group is 90.38%,while it is 72.00% in the control group.The comparison has statistic meaning(P0.05).After the treatment,patients' left ventricular end-systolic diameter and left ventricular end-diastolic diameter decrease,patients' stamina in the 6-minutes-walk experiment has increased.The comparison has statistic meaning(P0.05).Conclusion:The combined use of βB and ACEI can get a better treatment effect on the basis of conventional heart failure treatment.
出处
《医学理论与实践》
2012年第21期2596-2597,共2页
The Journal of Medical Theory and Practice