美林混悬液与安痛定注射液治疗上感发热患儿的临床观察

Clinical observation on the motrin suspension and antondine injection in the treatment of upper respiratory tract infection with fever in children

目的:观察比较美林混悬液与安痛定注射液治疗上呼吸道感染伴发热患儿的临床疗效。方法:选择伴有发热症状的上呼吸道感染患者100例(腋下体温≥39℃),分别给予口服美林混悬液与安痛定注射液,观察给药后不同时间段的退热情况及副反应。结果:在给药后第1小时,两组患儿退热速度接近,而美林混悬液组患儿在2小时后体温接近正常且维持8小时;安痛定注射液在用药后体温稍下降,未能降至正常,且4小时后体温回升。美林混悬液对其他伴随症状缓解较安痛定明显,如咽痛、头疼等。结论:美林混悬液退热作用强,维持时间长,对咽痛、头痛的缓解疗效较安痛定显著。

Objective：To observe and compare the clinical efficacy of Motrin suspension and Antondine injection in the treatment of upper respiratory tract infection with fever in children. Methods： 100 selected patients of upper respiratory tract infections accompanied by fever symptoms （ axillary temperature≥39℃） were given oral Motrin suspension and Antondine injection respectively to observe defervescence and side effects after administration in different time periods. Results： 1 hour after administration, the speed of defervescence in two groups of children with fever was close to each other. The body temperature of children in Motrin suspension group was close to normal two hours later and maintained for 8 hours; the body temperature of children in Antondine injection group was slightly decreased but failed to fall to normal level, and rebounded after 4 hours. Motrin suspension was more effective than Antondine to relieve symptoms,such as sore throat and headache. Conclusion： Motrin suspension had powerful antipyretic action with a long duration,and more significant efficacy on relief of sore throat and headache.