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维生素D受体Bsm1及Taq1基因多态性与非小细胞肺癌易感性的关系 被引量:3

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摘要 目的探讨维生素D受体(VDR)Bsm1及Taq1基因多态性与本地区非小细胞肺癌(NSCLC)易感性的关系。方法选择144例河北省秦皇岛籍汉族NSCLC患者(NSCLC组)和142例健康查体成人(对照组),两组均抽取空腹外周静脉血,采用PCR-限制性片段长度多态性的方法检测VDR的Bsm1、Taq1等位基因多态性。结果两组VDR的Bsm1、Taq1等位基因多态性分布均无显著差异。结论 VDR基因Bsm1、Taq1位点多态性与本地区NSCLC发病风险无明显关联。
出处 《山东医药》 CAS 2012年第43期40-41,共2页 Shandong Medical Journal
基金 秦皇岛市科学技术研究与发展计划立项项目(201101A259)
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参考文献6

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同被引文献17

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  • 7崔健,陈虹,黄秉仁.维生素D受体最新研究进展[J].生理科学进展,2011,42(2):95-99. 被引量:45
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  • 10杨雁鸿,周文文,唐利娟,齐曦明,侯燕燕,才丽娜,潘福栋,彭勇.维生素D受体基因多态性与吸烟因素交互作用对非小细胞肺癌发生的影响[J].中国老年学杂志,2013,33(16):3844-3846. 被引量:5

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