宫瘤消胶囊应用于子宫肌瘤剔除术后预防复发的疗效观察

Observation on the curative effect of Gongliuxiao capsule for preventing recovery of hysteromyoma after myomectomy

目的:探讨子宫肌瘤剔除术后应用宫瘤消胶囊预防复发的疗效。方法:选择2007年1月～2009年1月行子宫肌瘤剔除术的患者,随机分为干预组和观察组,均于术前月经第三天采集静脉血,检测雌激素(E2)和孕激素(P)水平。干预组术后给予口服宫瘤消胶囊,3粒/次,3次/日,1个月经周期为1个疗程,连续服用3个疗程,观察组未给予特殊治疗,二者皆术后半年随访1次,共随访3年。以上两组患者均于术后3月、6月时月经第3天采血测E2和P水平。结果:干预组和观察组随诊过程中发现干预组的复发率明显低于观察组(P<0.05)。两组术前测得E2和P水平无统计学差异(P>0.05),术后3月测得E2和P水平有统计学差异(P<0.05),术后6月测得E2和P水平比较无统计学差异(P>0.05)。结论:宫瘤消胶囊应用于子宫肌瘤剔除术后对预防复发有积极作用。

Objective：To explore the curative effect of Gongliuxiao capsule for preventing recovery of hysteromyoma after myomectomy.Methods：The patients who underwent myomectomy from January 2007 to January 2009 were selected and randomly divided into intervention group and observation group,venous blood samples were obtained on the third day of menstrual cycle before myomectomy,the levels of estrogen and progestogen were detected.The patients in intervention group were treated with oral administration of Gongliuxiao capsule after myomectomy,three grains once,three times a day,one course of treatment was a menstrual cycle,the patients were treated for successive three courses;the patients in observation group didn＇t receive any special treatment.All the patients were followed up once half a year for three years.The blood levels of estrogen and progestogen in the two groups were detected on the third day of menstrual cycle at 3 and 6 months after myomectomy.Results：The recurrence rate in intervention group was significantly lower than that in observation group（P0.05）;there was no significant difference in the levels of estrogen and progestogen between the two groups before myomectomy（P0.05）,but there was significant difference in the levels of estrogen and progestogen between the two groups at 3 months after myomectomy（P0.05）,while at 6 months after myomectomy,there was no significant difference（P0.05）.Conclusion：Gongliuxiao capsule plays an active role for preventing recovery of hysteromyoma after myomectomy.