中西医结合治疗细菌性肝脓肿51例临床观察

Clinical Observation of Integrative Medicine for 51 Cases of Bacterial Liver Abscess

目的观察中西医结合治疗细菌性肝脓肿的临床疗效。方法将97例细菌性肝脓肿患者随机分为治疗组51例和对照组46例,对照组给予抗感染,同时补充电解质、维生素、加强营养支持;治疗组在对照组基础上给予清肝消痈汤或生脉饮治疗。两组连续治疗28天后观察临床疗效,并检测治疗前、治疗后7天、14天、28天两组患者白细胞(WBC)、血小板(PLT)、血红蛋白(Hb)、丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、白蛋白(ALB)、总胆红素(TBiL)及血肌酐(SCr)水平。结果治疗组临床疗效总有效率100%,对照组为60.8%,治疗组总有效率明显优于对照组(P<0.05);治疗后7天两组ALT、AST、SCr水平比较差异均有统计学意义(P<0.05),其他指标差异无统计学意义(P>0.05);治疗后14天两组WBC、PLT、Hb、ALT、AST水平比较差异均有统计学意义(P<0.05);治疗后28天治疗组患者各项指标均恢复正常水平。结论中西医结合治疗细菌性肝脓肿疗效确切,优于单纯西医治疗。

Objective To observe the therapeutic effect of integrative medicine on bacterial liver abscess （B LA） .Methods Ninety seven BLA patients were randomized into the treatment group （5 1cases） and control group （4 6cases） .Anti-infections agents , as well as electrolytes ,v itamins, and nutritional support were given to both groups.Patients in the treatment group were added with Qinggan Xiaoyong Decoction （ decoction to clear the liver and disperse the welling-abscess ） or Shengmai Yin o- ral liquid , one dosage daily.One treatment course lasted for 7days.The white blood cell （W BC） count, platelet （P LT） count, hemoglobin （H b） , alanine aminotransferase （A LT） , aspartate aminotransferase （A ST） ,a lbumin（ ALB） , total bilirubin （T BiL） and creatinine （C r） were detected.The therapeutic effect was observed after 4courses of treatment.Results The to- tal effective rate of the treatment group （1 00%） was superior to that of the control group （6 0.8%） （ P〈0.05 ） .The differences between groups were statistically significant in ALT , AST and Cr after 7days of treatment （ P〈0.05 ） .The differences between groups were statistically significant in WBC ,P LT, Hb, ALT and AST after both 14days and 28days of treatment （ P〈0.05 ） .Conclusion Integrative medicine is more effective for BLA than treatment of only western medicine.