肝硬化并食管静脉曲张破裂出血患者血清NO、ACE、钠及血小板计数的变化研究

目的探讨肝硬化并食管静脉曲张破裂出血患者血清NO、ACE、钠及血小板计数的变化规律。方法选取2010年6月～2012年4月进行治疗的23例肝硬化并食管静脉曲张破裂出血患者为观察组,另选同期的23例肝硬化未发生出血的患者为对照组,将两组患者的血清NO、ACE、钠及血小板计数水平进行比较。结果观察组的血清NO、ACE高于对照组,钠及血小板计数均低于对照组,且再次出血者变化大于初次出血者,P均<0.05,有显著性差异。结论肝硬化并食管静脉曲张破裂出血患者的血清NO、ACE、钠及血小板计数呈现一定的波动,有助于了解出血情况。

Objective To investigate the variation for patients with cirrhosis and esophageal variceal bleeding in NO, ACE, sodium and the number ofplatelet. Methods 23 cases of liver cirrhosis and esophageal variceal bleeding for treatment from June 2010 to April 2012 were set as the observation group, 23 cases of cirrhosis of the liver the same period without bleeding were set as the control group. The serum NO, ACE sodium and platelet count levels in the two groups were taken for comparison. Results The serum NO, ACE in the observation group was higher than that in the control group. The sodium and platelet counts were lower than in the control group, and again the bleeding changes were greater than the initial bleeding, P〈0.05, there was significant difference. Conclusion Liver cirrhosis and esophageal variceal bleeding in patients with serum NO, ACE sodium and platelet count shows some fluctuations. It is good for the help of understanding the bleeding.