双介入治疗对晚期胰腺癌的疗效评价

目的评价晚期胰腺癌介入治疗的临床价值。方法收集做介入治疗的75例晚期胰腺癌患者。行介入化疗灌注,所有患者均接受1次或多次介入治疗,重复治疗者间隔时间为6周,所有患者均接受腹腔动脉和肠系膜上动脉化疗灌注。并对其中53例阻塞性黄疸患者介入灌注前行胆道支架置入术。结果介入化疗灌注术2个月后复查,75例患者中,完全缓解2例,部分缓解46例,疾病稳定24例,疾病进展3例,有效率(CR+PR)为64%;支架置入术后1个月复查阻塞性黄疸均缓解;全组患者生存时间3～43个月,平均18个月。结论双介入疗法治疗晚期胰腺癌能提高生活质量,延长患者的生存期。

Objective To evaluate the clinical value of advanced pancreatic cancer interventional treatment.Methods 75 patients with advanced pancreatic cancer who were done interventional treatment were collected in our department. Interventional chemotherapy infusion, all patients received one or more times interventional treatment, repeated treatment interval was 6 weeks, all patients underwent celiac artery and superior mesenteric arterial infusion chemotherapy. And 53 cases of obstructive jaundice involved in the perfusion before biliary stenting. Results Among the 75 cases, two months after the interventional therapy, there were 2 cases with complete remission,46 cases with partial remission,24 cases with stable disease,3 cases With progressive disease.The total effective rate was 64%.Stenting a review of obstructive jaundice were relieved.All the patients survival time from 3 to 43 months, an average of 18 months. Conclusion The palliative dual interventional therapy can improve quality of life and prolong survival period in late stage pancreatic cancer.