芍药甘草汤结合运动疗法治疗脑卒中后肘关节屈曲痉挛的临床研究

Clinical study on "Shaoyao Gancao Decoction" and physical therapy in treating poststroke elbow spasticity

目的观察芍药甘草汤化裁(芍甘汤)结合运动疗法治疗脑卒中后肘关节屈曲痉挛的临床疗效。方法将140例脑卒中后肘关节屈曲痉挛患者随机分为治疗组(芍甘汤结合运动疗法组)、对照1组(运动疗法组)和对照2组(巴氯芬结合运动疗法组),疗程均为3周。结果治疗组患者上肢肌张力改善的总有效率为89.7%,与对照1组42.5%、对照2组72.5%比较差异均有统计学意义(P<0.01)。治疗组的疼痛评分治疗前后差值与对照1组、对照2组比较差异有统计学意义(P<0.01)。治疗组治疗前后上肢肿胀评分差值与对照1组、对照2组比较差异有统计学意义(P<0.01)。治疗组治疗前后Berg平衡量表差值,与对照2组比较差异有统计学意义(P<0.05)。结论芍甘汤结合运动疗法可以缓解脑卒中患者肘关节屈曲痉挛、疼痛和肿胀的作用,提高患者的平衡及转移能力。

Objective To observe the clinical efficacy of ＂Shaoyao Gancao Decoction＂ and physical therapy in the treatment of poststroke elbow spasticity.Methods One hundred and forty subjects were randomized into three groups： group A in which 60 cases were treated by ＂Shaoyao Gancao Decoction＂ and physical therapy,group B in which 40 cases were treated by physical therapy only,and group C in which 40 cases were treated by physical therapy and baclofen,with a course of three weeks.Results The total effective rate was 89.7% in group A,42.5% in group B and 72.5% in group C,with differences between group A and groups B and C（P0.01）.After treatment,there were significant differences in pain score and tumefaction score of upper limb between group A and groups B and C（P0.01）.The difference of Berg balance scale（BBS） was significant between groups A and C（P0.05）.Conclusion ＂Shaoyao Gancao Decoction＂ and physical therapy can relieve poststroke elbow spasticity,pain and tumefaction.