小败毒膏质量标准研究

Studies on Quality Standards for Xiaobaidu Slurry

目的:建立小败毒膏质量标准。方法:采用薄层色谱法进行定性鉴别,鉴别了方中大黄、黄柏、陈皮、赤芍和甘草,并建立山银花的检查方法;采用高效液相色谱法测定小败毒膏中芍药苷的含量。结果:薄层色谱斑点清晰,重复性好,芍药苷在0.182 4～3.64 80μg线性关系良好,平均回收率为98.4%,RSD 1.98%。结论:方法简便易行,重复性好,适用于小败毒膏质量控制。

Objective： To establish the quality standards for Slurry of Xiaobaidu. Method： The thin- layer chromatography was adopted for qualitative identification. Paeoniflorin was detected by HPLC. Result： The determination method for the content of paeoniflorin was established. The calibration curve of paeoniflorin was linear in the range of 0. 182 4-3. 648 0μg. The average recovery of paeoniflorin was 98.4%. Conclusion： The method is simple, accurate and reproducible. It can be used for the quality control of compound Xiaobaidu Slurry.