收缩期左房应变及应变率与阵发性房颤射频消融治疗效果的研究

Correlation of Systolic Left Atrial Strain and Strain Rate with the Efficacy of Radiofrequency Ablation for the Treatment of Paroxysmal Atrial Fibrillation

【目的】用基于斑点追踪技术的应变及应变率来评价房颤患者左房机械功能，并探讨其与射频消融治疗效果的关系。【方法】对拟行射频消融治疗的42例阵发性房颤患者术前测量收缩期左房应变及应变率，追踪观察患者射频消融术治疗效果。分析收缩期左房应变及应变率与射频消融治疗效果的关系。【结果】42患者均顺利完成射频消融治疗，在3个月追踪期内13例患者出现房颤复发（33．3％），余29例维持窦性心率。复发组年龄、性别比、左房内径、左房客积、左室射血分数与无复发组比较均无显著性差异（P〉0.05）；复发组左房收缩期总体应变及应变率均低于无复发组，其差异有统计学意义（P〈0.05）。【结论】收缩期左房应变及应变率与房颤患者射频消融术成功率有明显关系。

[Objective]To evaluate the left atrial mechanical function of patients with atrial fibrillation by using strain and strain rate based on speckle tracking technique, and to explore its correlation with the efficacy of radiofrequency ablation . [Methods]Totally 42 patients with paroxysmal atrial fibrillation（PAF） scheduled for radiofrequency ablation were enrolled in this study. Systolic left atrial strain（LAS） and strain rate（LASR） were measured before the operation. The efficacy of radiofrequency ablation was followed up. The correlation of LAS and LASR with the efficacy of radiotherapy ablation was analyzed. [Results] All 42 patients under- went radiofrequency ablation successfully. The recurrence of atrial fibrillation occurred in 13 patients（33.3%） during 3 months of follow up. Other 29 patients were sinus heart rate. There was no significant difference in age, sex ratio, left atrial diameter, left atrial volume and left ventricular ejection fraction between recurrence group and non-recurrence group（ P〉0.05）. Total LAS and LASR in recurrence group were lower than those in non-recurrence group, and there were significant differences（ P〈0.05）. [Conclusion] LAS and LASR are obviously correlated with the successful rate of radiofrequency ablation for patients with atrial fibrillation.