ECT联合肿瘤标志物检测诊断老年肺癌骨转移的临床观察

ECT combined with tumor markers detection and diagnosis of lung cancer in elderly bone metastases clinical observation

目的：探讨分析ECT（放射性按素骨显像）联合肿瘤标志物检测诊断老年肺癌骨转移的价值，从而来提高老年肺癌骨转移的诊断率。方法：选择于2007年3月-2010年12月在我院接受治疗的老年肺癌168例，随机分成对照组和观察组各84例，对照组患者应用ECT单独检测方法，观察组忠者采用ECT联合肿瘤标志物检测方法，然后比较两种检测方法在老年肺癌骨转移诊断中敏感性、特异性、准确性的差异。结果：结果发现对照组和观察组老年肺癌骨转移诊断中敏感性、特异性、准确性分别为64．4%、85．7％、71．8％与87．8％、96．1％、90．6％，两组比较差异具有统计学意义（P〈0．05）。结论：ECT联合肿瘤标志物检测诊断老年肺癌骨转移具有十分重要的临床应用价值，在今后的临床诊断中应普遍运用。

Objective：To investigate the ECT （ analysis of radionuclide bone imaging ） combined with tumor marker detection in the diagnosis of senile lung cancer bone metastases value, so as to improve the diagnosis rate of senile lung cancer bone metastasis. Methods：From 2007 March -2010 year in December in our hospital for treatment of senile lung cancer 168 cases, were randomly divided into observation group and control group with 84 cases in each group were treated with ECT alone, detection methods, the observation group were treated by ECT and tumor marker detection method,and then the comparison of two detection methods in the diagnosis of bone metastasis of lung cancer in the elderly patients the sensitivity, specificity,accuracy differences. Result：Observation group and control group in diagnosis of bone metastasis of lung cancer in the elderly patients of sensitivity,specificity,accuracy were 64.4% ,85.7% ,71.8% and 87.8% ,96.1% ,90.6% ,two groups with significant difference （P〈0.05）. Conclusion：ECT combined detection of tumor markers in diagnosis of lung cancer in the elderly patients of bone metastases has very important value in clinical application,in the future should be widely applied in clinical diagnosis.