摘要
脊髓损伤治疗获得明显进展是在20世纪90年代,包括人体脊髓损伤病理改变和继发损伤的认识,强调伤后8小时以内早期治疗,药物治疗有MP、GM-1,NGF等,24-48小时内早期减压可减轻水肿有助于脊髓功能恢复,早期MP+减压效果最好,马尾断裂应早期修复,实验研究表明脊髓横断以轴突生长抑制抗体IN-1,神经营养素3和末梢神经由白质至灰质交叉移植,均可使动物恢复脊髓功能。
The advanced progressin
the treatment of spinal cord injury was the entity since ninety decade of the 20th century included the knowledge of the pathology of spinal cord injury and secondary injury to the spinal cord after injury. Early treatment within 8 hours after injury was specially emphasized. Therapeutic agents are MP, GM -1, NGF and so on. The edema of the spinal cord may re-
lieved by early decompression 24 -48 hours after injury to get better recovery. Early MP and decompression give the best results. Transection of cauda equina should be repaired early. The experimental research revealed that the transected spinal cord may get functional recovery after local usage of antibodies to neu-rite growth inhibitors or neurotrophin -3 or by cross grafting with peripheral nerve from white matter to gray matter distally.
关键词
脊髓损伤
治疗
疗效
spinal cord injury, progress in treatment