肝昏迷患者脑脊液中亚硝酸盐、硝酸盐测定的探讨

Determination of Nitrite.Nitrate in Cerebrospinal Fruid in patients with Hepatic Coma

目的:探讨脑脊液(CSF)K中一氧化氮(NO)在肝昏迷发病机理中的作用。方法:采用硝酸盐还原酶法将CSF中NO-3还原为NO-2,测定其中NO-2/HO-3含量。结果:肝昏迷组CSF中NO-2/NO-3含量与对照组相比有显著升高(P<001)。结论:NO在肝昏迷的发病机理中可能起一定作用。

Objective:To detect the function of nitric oxide to hepatic coma.Method :Determined nitrite/nitrate in cerebrospinal fluid by means of conversing nitrate into nitrite by nitrate reductase. Result :The consistency of nitrite/nitrate in group of hepatic coma was much higher than that of in contrast group.Conclusion: It is likely that nitric oxide take some action to hepatic coma .