急性期脑梗死患者红细胞免疫功能变化的特点

Changes of red cell immune function in patients with cerebral infarction at acute stage

目的 探讨急性期脑梗死患者红细胞免疫粘附功能变化的特点。方法 观察了 86例急性期脑梗死患者和6 3例正常对照者的红细胞免疫功能四项指标 :红细胞C3b受体花环率 ,红细胞免疫复合物花环率 ,血清中红细胞免疫粘附增强因子及红细胞免疫粘附抑制因子。结果 急性期脑梗死患者红细胞免疫功能变化的特点是红细胞C3b受体花环率降低 ,红细胞免疫复合物花环率升高 ,同时伴有血清中红细胞免疫粘附增强因子活性降低及红细胞免疫粘附抑制因子活性增强 ,红细胞免疫粘附功能低下。结论 本研究为探讨急性期脑梗死红细胞免疫功能变化的特点及拓宽脑梗死的防治途径提供了依据。

Objective To study and investigate the changes of red cell immune function in patients with cerebral infarction at acute stage.Methods red cell immune function in 86 patients with cerebral infarction at acute stage and 63 health persons:red cell C3b receptor cycle rates(RCR),red cell immune complex cycle rates(RICR), red cell immune adherence enhanced factor(RIAEF) and red cell immune adhevence inhibition factor(RIAIF) were determined.Results Compared by normal control group,RCR were decreased,RICR were increased,the serum RIAEF were decreased,and the serum RIAIF were increased in patients with cerebral infarction at acute stage.Red cell immune adherence function was decreased.Conclusions The study provided basis to investigate features of change of red cell immune function in patients with cerebral infarction at acute stage and widen preventation and treatment of cerebral infarction. [