辽宁省流脑流行病学分析

Epidemiolgic Analyse of Meningitis Meningococcal in Liaoning Provnce.

对辽宁省 195 0～ 1999年流脑的流行特征进行了分析。结果表明A群流脑多糖菌苗的使用 ,打破了我省每间隔 8年一次高峰的规律 ,大大降低了流脑的发病率 ,削平了流脑年龄别发病的第二个高峰 ,使城乡发病率之差逐年缩小 ,季节流行的特点无变化。血清学监测结果表明 ,菌苗使用后 ,人群杀菌抗体阳性率基本保持在 5 0 %以上 ,GMT在 1:2以上 ,虽未达到杀菌抗体临界保护值 ,但流行病学效果显著。带菌调查结果显示 ,健康人群的带菌率无明显变化 ,以B群为主 ,A群带菌率逐年下降 。

This paper analysed the epidemic charactor of meningitis menignococcal around using meningococcal polysecchaaride vaccine group A.Results showed that using meningococcal polyseccharide vaccine group A has broken the epidemic charactor,greatly reduced the morbidity,cut the second peak of age specific morbidity.The disparity of incidence between urban and rural have been getting small,but the seasonal peak has not become different.The surveillance of serologly and meningococcal carriage indicated there has been a significance negative crrelation between the meningitis meningococcal morbidity and BA antibody positive rate or GMT,a significance positive correlation between the meningitis meningococcal morbidity and meningococcal group A carriage rate too.The above mentione will provide certain scientific basis for epidemiological monitoring and forecasting of meningitis meningococcalafter using meningococcal polyseccharide vaccine group A.