期刊文献+

XELOX化疗方案对老年晚期食管癌患者生存质量的影响 被引量:6

下载PDF
导出
摘要 目的探讨采用XELOX化疗方案治疗老年食管癌晚期患者的临床疗效及其对生存质量的影响。方法选取2009年6月至2012年6月该院收治的老年食管癌晚期患者36例作为实验组,给予XELOX治疗;我院历史收治的老年食管癌晚期患者32例作为对照组,对照组进行FP法治疗。对患者的病情缓解情况、生活质量情况进行对比分析,并记录毒副反应情况。结果实验组患者的病情缓解率为50.0%,对照组为34.4%,差异有统计学意义(P<0.05)。实验组患者生活质量(Karnofsky)得分为(84.5±8.5)分,对照组为(68.7±9.2)分,差异有统计学意义(P<0.05)。实验组患者的化疗完成率为91.7%,对照组为75.0%,差异有统计学意义(P<0.05)。结论 XELOX化疗可使老年食管癌晚期患者临床症状明显减轻,且患者毒性反应小,临床疗效较好,可明显提高患者生存质量。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第22期4915-4916,共2页 Chinese Journal of Gerontology
  • 相关文献

参考文献5

二级参考文献18

  • 1李园,武晓勤,崔慧娟,谭煌英.紫杉醇联合化疗方案治疗晚期胃癌的临床研究[J].中华肿瘤杂志,2004,26(9):562-564. 被引量:19
  • 2Webb A, Canningham D, Scarffe JH, et al. Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer. J Clin Oncol, 1997, 15:261-267.
  • 3Waters JS, Norman A, cunningham D, et al. Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial. Br J Cancer, 1999, 80:269-272.
  • 4Cocconi G, Carlini P, Gamboni A, et al. Cisplatin, epimbicin, leucovorin and 5-fluomuracil (PELF) is more active than 5- fluorouracil, doxorubicin and methotrexate (FAMTX) in advanced gastric carcinoma. Ann Oncol, 2003, 14 : 1258-1263.
  • 5Hundahl SA, Phillips JL, Menck UR, et al. The National Cancer Data Base Report on poor survival of U. S. gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer staging, proximal disease, and the "different disease" hypothesis. Cancer, 2000, 88:921-932.
  • 6Ichikura T, Tomimatsu S, Uefuji K, et al. Evaluation of the new American Joint Committee on Cancer/International Union Against Cancer classification of lymph node metastasis from gastric carcinomain in comparison with the Japanes classification. Cancer, 1999, 86:553-558.
  • 7Earlel CC, Maroun JA. Adjuvant chemotherapy after curative resection for gastric cancer in non-Asian patients: revisiting a meta-analysis of randomised trials. Eur J Cancer, 1999, 35 : 1059-1064.
  • 8Mari E, Floriani I, Tinazzi A, et al. Efficacy of adjuvant chemotherapy after curative resection for gastric cancer: a meta-analysis of published randomised trials. Ann Oncol, 2000, 11:837-843.
  • 9Herskovic A, Al-sarraf M. Contribution of 5-floroorucial and radiation oncology in esophageal in esophageal cancer. Sem in Rad Oncol, 1997,7: 283 - 290.
  • 10Sionov RV,Haupt Y.The cellular response to p53:the decision between 1ife and death[J].Oncogene,1999,18:6145-6157.

共引文献22

同被引文献60

引证文献6

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部