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特殊类型孕激素在早产预防中的应用 被引量：5

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摘要 早产是导致新生儿死亡及短期或长期致残的主要原因，其中40％的早产发生在妊娠34周前，20％发生在32周前。妊娠34周前的早产占围产儿死亡及病率的50％。如何延长孕周以降低围产儿死亡率及病率是早产防治的关键。目前常用的宫缩抑制剂可以适当延长先兆早产患者的妊娠天数，但早产的处理关键在于如何提前筛选早产的高危人群，通过预防措施降低其进入早产临产阶段的概率，从而在真正意义上延长孕周。
作者 段涛 杨慧霞 胡娅莉 贺晶 王子莲 张建平 孙丽洲 周秭
机构地区 中华医学会围产医学分会
出处 《中华围产医学杂志》 CAS 北大核心 2012年第11期656-659,共4页 Chinese Journal of Perinatal Medicine
关键词 早产预防 孕激素 围产儿死亡率 妊娠34周 应用 新生儿死亡 宫缩抑制剂 先兆早产
分类号 R714.7 [医药卫生—妇产科学]
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参考文献21

  • 1WHO online data. (2009-12-01) [2011-03-30] http://apps.who. int/rhl/pregnancy _ childbirth/complications/preterm _birth/cd004947_gonza.
  • 2Meis PJ,Klebanoff M, Thom E,et al. Prevention ofrecurrent preterm delivery by 17-alpha hydroxyprogesteronecaproate. N Engl J Med, 2003,348:2379-2385.
  • 3Farine D,Mundle WR, Dodd J? et al. The use ofprogesterone for prevention of preterm birth. J ObstetGynaecol Can, 2008 ,30 : 67-77.
  • 4Society for Maternal Fetal Medicine Publications Committee.ACOG Committee Opinion number 419 October 2008(replaces no. 291,November 2003). Use of progesterone toreduce preterm birth. Obstet Gynecol, 2008,112 :963-965.
  • 5Society for Maternal-Fetal Medicine Publications Committee,with assistance of Vincenzo Berghella. Progesterone andpreterm birth prevention: translating clinical trials data intoclinical practice. Am J Obstet Gynecol,2012 ,206 : 376-386.
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同被引文献114

  • 1边旭明,董悦.早产的临床诊断与治疗推荐指南(草案)[J].中华妇产科杂志,2007,42(7):498-500. 被引量：121
  • 2Goldenberg RL,Culhane JF,Iams JD,et al.Epidemiology and causes of preterm birth[J].Lancet,2008,371:75-84.
  • 3Spong CY.Prediction and prevention of recurrent spontaneous preterm birth[J].Obstet Gynecol,2007,110:405-415.
  • 4ACOG.Practice Bulletin No.130:prediction and prevention of preterm birth[J].Obstet Gynecol,2012,120:964-973.
  • 5Iams JD.Prevention of preterm parturition[J].New Engl J Med,2014,370:254-261.
  • 6Sadler L,Saftlas A,Wang W,et al.Threatment for cervical intraepithelial neoplasia and risk of preterm delivery[J].JAMA,2004,291:2100-2106.
  • 7Zhong Y,Cahill AG,Macones GA,et al.The association between prepregnancy maternal body mass index and preteim delivery[J].Am J Perinatol,2010,27:293-298.
  • 8SOGC Clinical Practice Guideline.Uhrasonographic cervical length assessment in predicting preterm birth in singleton pregnancies[J].J Obstet Gynaecol Can,2011,33:486-499.
  • 9Owen J,Iams JD.What we have learned about cervical ultrasound.NICH Maternal-Fetal Medicine Unit Network[J].Semin Perinatol,2003,27:194-203.
  • 10ACOG Committee Opinion No.419 Use of progesterone to reduce preterm birth[J].Obstet Gynecol,2008,112:963-965.

引证文献5

二级引证文献374

中华围产医学杂志
2012年 第11期

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