医用隐形抗菌膜预防食管癌放射性皮肤反应的效果

Effect of medical invisible antibacterial film to prevent radioactive skin injury of patients with esophagus cancer

目的探讨医用隐形抗菌膜预防食管癌放射性皮肤损伤的效果。方法将187例接受放疗的食管恶性肿瘤患者随机分为两组（随机数字法），对照组82例采用常规护理，观察组105例在对照组的基础上于放疗前后予照射野皮肤局部喷雾医用隐形抗菌膜，比较两组患者局部皮肤损伤情况。结果两组放射性皮肤损伤情况比较，对照组0级10例（12．2％），1级13例（15．9％），2级42例（51．2％），3级12例（14．6％），4级5例（6．1％）；观察组0级67例（63．8％），1级27例（25．7％），2级8例（7．6％），3级3例（2．9％），4级0例（0．0％）。经秩和检验差异有统计学意义（Z=4．330，P=0．000）。结论医用隐形抗菌膜能降低食管肿瘤患者放疗后皮肤损伤的发生率及损伤程度。

Objective To observe the effect of medical invisible antimicrobial film to prevent radioactive skin injury of patients with esophagus cancer. Methods 187 patients with esophagus cancer were randomly divided into two groups： the control group with 82 cases and the observation group with 105 cases. The control group received conventional nursing while the observation group received medical invisible antimicrobial film before and after radiotherapy in addition, and skin injury of two groups was compared. Results There were 10 cases （ 12.2% ） of zero level, 13 cases （ 12.2% ） of one level, 42 cases （51.2%） of two level, 12 cases （14.6%） of three level, and 5 cases （6. 1% ） of four level in the control group. There were 67 cases （63.8%） of zero level, 27 cases （25.7%） of one level, 8 cases （7.6%） of two level, 3 cases （2.9%） of three level, and 0 case （0.0%） of four level in the observation group. The differences of Rank sum test was statistically significant （Z = 4. 330, P = 0. 000）. The frequency and severity of skin injury in observation group was obviously lower than that of control group. Conclusions Medical invisible autimicrobiaf film can effectively reduce the incidence rate and severity of skin injury after radiation.