怀化市健康人群麻疹抗体水平监测

Surveillance of atibody lvel of measles among healthy population in Huaihua City

目的了解怀化市健康人群麻疹抗体水平和人群免疫状况,为有效地实施麻疹预防措施和控制策略提供科学依据。方法 2010年对7个年龄组共347名健康人群采集静脉血,用酶联免疫吸附试验法进行麻疹特异性LgG抗体水平检测。结果麻疹抗体阳性率为86.74%。不同区(县)麻疹抗体阳性率之间差异无统计学意义(χ2=3.47,P>0.05);不同年龄组麻疹抗体阳性率差异有统计学意义(χ2=41.64,P≤0.05);男性与女性麻疹抗体阳性率之间差异无统计学意义(χ2=0.37,P>0.05);城市与农村抗体阳性率之间差异无统计学意义(χ2=0.49,P>0.05)。结论该市健康人群麻疹抗体水平低于95%,为实现消除麻疹目标,应在大年龄组儿童、育龄妇女及成人中进行麻疹疫苗接种,提高并维持全人群较高的麻疹抗体水平。

[Objective] To understand the measles antibody level of healthy population in Huaihua City and immunization status of people,and provide a scientific basis for the effective implementation of measles prevention and control strategies.[Methods]In 2010,venous blood samples of 347 healthy people from 7 age groups were collected for the detection of specific IgG antibody levels of measles by enzyme linked immunosorbent assay method.[Results] The positive rate of measles antibody was 86.74%.The positive rate of measles antibody was significantly different between different districts（counties）（χ2=3.47,P0.05）;the positive rate of measles antibody between different age groups was significantly different（χ2=41.64,P≤0.05）;measles antibody positive rate was not significantly different genders（χ2=0.37,P0.05）;and that was not significantly different between urban and rural area（χ2=0.49,P0.05）.[Conclusion]The measles antibody level in healthy population is less than 95%in this city.In order to achieve the goal of measles elimination,measles vaccination should be implemented in the older age group of children,women of childbearing age and adult so as to enhance and sustain high measles antibody level in the whole population.