脉搏波早期预测妊娠高血压综合征的价值探讨

Early Predictive Value of Pulse Wave Monitoring for Hypertensive Disorders in Pregnancy

目的:探讨脉搏波监测系统预测妊娠高血压综合征(简称妊高征)的临床价值。方法:将1380例孕20～38周孕妇随意愿分为监测组872例和未监测组508例。监测组从孕20周开始进行脉搏波无损伤监测,每4周监测1次;预测阳性者432例,每2周监测1次,并分为干预组(n=222)和对照组(n=210),干预组除给予生活指导外增加药物预防性治疗。结果:妊高征的发生率监测组为5.39%,未监测组为9.45%,两组比较,P<0.05。预测阳性并接受早期干预者中妊高征的发生率低于预测阳性而未接受早期干预者(4.5%与10.0%,P<0.025)。结论:脉搏波监测系统可以预测妊高征的发生,对预测阳性者早期干预可以降低妊高征发生率。

Objective：To evaluate the predictive value of pulse wave monitoring for hypertensive disorders in pregnancy. Methods：A total of 1380 patients with gestional weeks of 20-38 were enrolled. They were assigned either into monitoring group （n = 872） or non-monitoring group （n = 508）. Participants in monitoring group were monitored by pulse wave from 20th week every 4 weeks. In the monitoring group, 432 participants were predicted to be at high risk of hypertensive disorders, and then they were randomized into intervention group （n = 222, they were given preventive drugs and life guidance） or non-intervention group （n= 210）. The incidences of hypertensive disorders were monitored during the pregnancy and compared among all the groups. Results： The incidences of hypertensive disorders in the monitoring group and non-monitoring group were 5.39% and 9.45% （P〈0.0）5）. The incidence of hypertensive disorders in the intervention group was 4.5%, while that in the nonintervention group was 10.0 % （P〈0.05）. Conclusions： Pulse wave monitoring can be used for predicting hypertensive disorders in pregnancy, and early clinical intervention can reduce the morbidity.