期刊文献+

脂肪干细胞在皮肤组织创面修复中的研究进展

Progress of Adipose Derived Stem Cells in Skin Repair and Regeneration
下载PDF
导出
摘要 严重机械压榨伤、大面积烧伤后常出现大面积的皮肤组织创面,由于皮肤软组织大量缺损,深部组织过多暴露,伤日污染严重,导致创面难以愈合。皮瓣或皮片移植术作为临床上较为常用的治疗手段,虽然其成功率高、费用较低,但由于存在供皮区组织缺损、瘢痕形成以及疼痛等缺点,从而限制了其临床应用。真皮替代物缺乏血管结构,血管化过程慢,并且缺乏抗感染能力,导致移植成活率较低。
出处 《中国临床医学》 2012年第5期566-569,共4页 Chinese Journal of Clinical Medicine
  • 相关文献

参考文献1

二级参考文献14

  • 1Janes SM,Lowell S,Hutter C.Epidermal stem cells.J Pathol,2002,197(4):479-491.
  • 2Kucia M,Dawn B,Hunt G,et al.Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction.Cir Res,2004,95(5):1191-1199.
  • 3Vasyutina E,Stebler J,Brand-Saberi B,et al.CXCR4 and Gabl cooperate to control the development of migrating muscle progenitor cells.Genes Dev,2005,19(18):2187-2198.
  • 4Togel F,Isaac J,Hu Z,et al.Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury.Kidney Int,2005,67(5):1772-1784.
  • 5Imitola J,Raddassi K,Park KI.Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1 alpha/CXC chemokine receptor 4 pathway.Proc Natl Acad Sci USA,2004,101(52):18117-18122.
  • 6司徒振强,吴军正.细胞培养.2版.上海:世界图书出版公司,2007:58-59.
  • 7El Ghalbzouri A,Hensbergen P,Gibbs S,et al.Fibroblasts facilitate re-epithelialization in wounded human skin equivalents.Lab Invest,2004,84(1):102-l 12.
  • 8Singer AJ,Clark RA.Cutaneous wound healing.N Engl J Med,1999,341 (10):738-746.
  • 9Pablos JL,Amara A,Bouloc A,et al.Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin.Am J Pathol,1999,155(5):1577-1586.
  • 10Petit I,Goichberg P,Spiegel A,et al.Atypical PKC-zeta regulates SDF-1 -mediated migration and development of human CD34+ progenitor cells.J Clin Invest,2005,115(1):168-176.

共引文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部