氨溴特罗治疗儿童急性支气管炎临床观察

Therapeutic Effect of Ambroxol and Clenbuterol Oral Solutions on Acute Bronchitis in Children

目的:探讨氨溴特罗口服液治疗儿童急性支气管炎的效果。方法:300例急性支气管炎患儿随机分成两组各150例。两组均在控制感染的基础上,治疗组口服氨溴特罗,对照组口服复方福尔可定,疗程5 d。观察两组临床疗效、不良反应和依从性。结果:治疗5 d后,治疗组总有效率(93.33%)明显高于对照组(84.67%),差异有统计学意义(P<0.05);咳嗽、痰量、痰黏稠度、喘息评分、不良反应发生率和依从性等方面比较,差异均有统计学意义(P<0.01或0.05)。结论:氨溴特罗治疗急性支气管炎疗效显著,安全可靠,依从性好。

Objective： To evaluate the therapeutic effects of ambroxol and clenbuterol oral solutions on acute bronchitis in children.Method： Totally 300 cases with acute bronchitis were randomly divided into the treatment group（150 cases） and the control group（150 cases）.On the basis of anti-inflammatory therapy,ambroxol and clenbuterol oral solutions were given in the treatment group and pholcodine syrups were used in the control group for 5 days.The therapeutic effects,adverse reactions and compliance of the two groups were assessed.Result： After the treatment,the total effective rate of the treatment group（93.33%）was higher than that of the control group（84.67%）（P0.05）.The effects on cough,sputum volume,sputum viscosity and wheezing were much better in the treatment group than those in the control group（P0.01）.There were significant statistic differences in the adverse reactions and compliance between the two groups（P0.05）.Conclusion： Ambroxol and clenbuterol oral solutions are safe,convenient and highly effective in the treatment of acute bronchitis in children.