摘要
[ Objective] The paper was to study the acute toxicity of Oxytropis Kansuensis Bunge on rats. [ Method ] Forty rats were randomly divided into two gToups: control group (distilled water) and trial group (water extract of 0. Kansuens/s) to carry out the acute toxicity experiment. The trial group was supplied with the maximum dose (6.0 g/ml,0.8 ml/20 g) twice per day for continuous 7 d. [Result] The maximal tolerance dose of rats to water extract of O. Kansuens/s was more than 480 g/kg. Feeding rats with O. Kansuens/s would not lead to the death of rats within short time (7 d) and no obvious macroscopic pathological changes in the viscera of rats could be seen in naked eyes. [Condusion] The study provided theoretical basis for full use of O. Kansuens/s resources.
[ Objective] The paper was to study the acute toxicity of Oxytropis Kansuensis Bunge on rats. [ Method ] Forty rats were randomly divided into two gToups: control group (distilled water) and trial group (water extract of 0. Kansuens/s) to carry out the acute toxicity experiment. The trial group was supplied with the maximum dose (6.0 g/ml,0.8 ml/20 g) twice per day for continuous 7 d. [Result] The maximal tolerance dose of rats to water extract of O. Kansuens/s was more than 480 g/kg. Feeding rats with O. Kansuens/s would not lead to the death of rats within short time (7 d) and no obvious macroscopic pathological changes in the viscera of rats could be seen in naked eyes. [Condusion] The study provided theoretical basis for full use of O. Kansuens/s resources.
基金
Supported by Major Directional Project of Chinese Academy of Sciences( KGCX2-SW-213-08)
National Natural Science Foundation of China ( NS-FC. NO. 20775083)~~