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替吉奥联合放射治疗治疗食管癌70例的临床分析 被引量:1

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摘要 目的:观察替吉奥联合放射治疗治疗食管癌的临床疗效。方法:将病理证实的食管癌患者70例随机分为对照组和治疗组。对照组放射治疗选用6MV-X线5~7个拉弧旋转等中心照射,80%剂量曲线包绕PTV为2.0Gy/次,总量DT70Gy/70次/7周。治疗组在对照组的基础上加用替吉奥,按体表面积计算用药量(40~60mg/次),用法为每日2次,早晚餐后口服,连续给药28天,休息14天为1个治疗周期。结果:治疗组疗效明显高于对照组,差异有统计学意义(P<0.05)。胃肠道反应和血象变化两组比较有统计学意义(P<0.05)。结论:食管癌术后采用替吉奥联合放射治疗的疗效明显好于单纯放射治疗。
作者 高庆
出处 《中国社区医师(医学专业)》 2012年第31期71-72,共2页
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  • 1Shirasaka T,Shimamoto Y,Ohshimo H,et al.Development of a novel form of an oral 5-fluorouracil derivative(S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators[J].Anticancer Drugs,2006,7:548-57.
  • 2Diasio RB.Clinical implications of dihydropyrimidine ehydrogenase inhibition[J].Oncology(Williston Park),1999,13(Suppl):17-21.
  • 3侯良宝,郭丙坤,李玉环.放疗与放化综合治疗晚期食管癌220例对比分析[J].河南肿瘤学杂志,1996,9(3):196-197. 被引量:3
  • 4E Van Cutsem,Hoff PM,Harper P,et al.Oral capecitabine vs intravenous 5-fluorouracil and leucovorin:integrated efficacy data and novel analyses from two large,randomized,phaseⅢ trials[J].British Journal of Cancer,2004,90:1190-1197.
  • 5Koji Harada,Shin-ichi Kawaquchi,Supriatno,et al.Combined effects of the oral fluoropyrimidine anticancer agent,S-1 and radiation on human oral cancer cells[J].Oral Oncology.2005,40(7):713-719.
  • 6Mingione V,oliveiva M,Prasad D,et al.Gamma knife surgery for melanoma metastases in the barin[J].J Neuorsurg,2002,96:544-551.
  • 7Aragane H,Suchi K,Shimomura M,et al.Severe bone marrow suppression during adjuvant chemotherapy for gastric cancer by S-1 and its possible relationship to dihydropyrimidine dehydrogenase deficiency[J].Gan To Kagaku Ryoho,2010,37(1):131-133.

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