摘要
目的:探讨狼疮性肾炎(LN)的临床与病理特点,了解病理改变与临床表现之间的联系。方法:选择在我院治疗的150例LN患者为研究对象,分析其病理与临床表现。结果:150例患者中,Ⅱ型10.0%,Ⅲ型16.0%,Ⅳ型52.0%,V型20.0%,Ⅵ型2.0%,未见I型病例。Ⅳ型发生率明显高于其他类型,差异有显著性,P<0.05;肾病综合征型和肾功能不全发生率以Ⅳ型最高,与其他组比较具有统计学意义,P<0.05。结论:LN的病理类型与临床表现关系密切,肾穿刺活检术对判断疾病活动性,指导临床治疗具有重要意义。
Objective：To investigate the clinical and pathologic features of lupus nephritis（LN）,understanding the link between pathological changes and clinical manifestations.Methods：In our hospital 150 cases of LN patients for the study,analysis of the pathological and clinical manifestations.Results：The results of 150 patients,type II 10.0%,16.0% of type Ⅲ and type Ⅳ 52.0%,V-type 20.0%,2.0% VItype,no type I cases.Type Ⅳ were significantly higher than other types,there is significant difference（P0.05）;nephrotic syndrome and renal insufficiency,the incidence of type Ⅳ highest compared with the other groups was statistically significant（P0.05）.Conclusion：LN pathological types and clinical manifestations are closely related to renal biopsy to determine the disease activity,guide clinical treatment of great significance.
出处
《中国医药导刊》
2012年第10期1737-1737,1739,共2页
Chinese Journal of Medicinal Guide
关键词
狼疮性肾炎
临床
病理
Lupus Nephritis
Clinical
Pathological
