氯沙坦联合银杏达莫治疗糖尿病肾病98例临床分析

Clinical Analysis of 98 Cases for Treating Diabetic Nephropathy(DN) by Losartan Combined with Ginkgo Leaf Extract and Dipyridamole

目的:探讨氯沙坦联合银杏达莫治疗糖尿病肾病的临床疗效。方法:将196例糖尿病肾病患者随机分为观察组和对照组各98例,观察组采用氯沙坦联合银杏达莫治疗,对照组采用氯沙坦治疗,比较两组临床疗效。结果:观察组总有效率91.84%;对照组总有效率75.51%,两组比较有显著性差异(P<0.01)。两组患者治疗后各项观察指标与治疗前比较均有显著性差异(P<0.01);治疗后观察组改善更为明显,与对照组比较有显著性差异(P<0.01)。结论:氯沙坦联合银杏达莫对糖尿病肾病患者的肾脏具有保护作用,疗效确切。

Objective：To investigate the Clinical effects in treating Diabetic nephropathy（DN） by.Methods：The 196 cases of diabetic nephropathy（DN） were randomly divided into two groups with Observation group and Control group,98 cases respectively.The Observation group was treated by Losartan combined with Ginkgo Leaf Extract and Dipyridamole,while the Control group was used to treat by Losartan,then to compare the treatment effects of two groups.Results：The treatment total effective rate of observation was 91.84%,while the total effective rate of control group was 75.51%,there were significant difference between two groups.（P0.01）.After Surgery,each data of oxidative stress in blood had significant differences than before the treatment for the two gropus：but the observation group had higher significant changes than control group：two groups had significant differences.（P0.01）.Conclusion：The treatment of Losartan combined with Ginkgo Leaf Extract and Dipyridamolecan protect the nephropathy of diabetic nephropathy patients with accurate and quite effective methods,worthy to widely used in clinical treatments.