摘要
目的:探讨检验尿生化指标对原发性骨质疏松症的治疗的评价价值。方法:回顾性分析我院收治的70例原发性骨质疏松的患者的临床资料,按照治疗方法的不同分为治疗组和对照组,对照组采用钙维生素D治疗,治疗组在对照组的基础上采用阿仑膦酸钠治疗,另选取健康体检组40例为正常组,测定病例组患者治疗前后及对照组的尿生化指标吡啶酚(PYD)、脱氧吡啶酚(DPD)、尿钙(Ca)及尿羟脯氨酸(HOP)。结果:病例组患者的PYD/Cr、DPD/Cr、Ca/Cr、HOP/Cr显著高于正常组,P<0.05。病例组治疗后的PYD/Cr、DPD/Cr较治疗前显著降低,P<0.05,且治疗组的改善效果要优于对照组,P<0.05。病例组治疗前后的Ca/Cr、HOP/Cr无显著性差异,P>0.05。治疗组和对照组无显著性差异,P<0.05。结论:PYD、DPD是原发性骨质疏松的较好的诊治指标,特异性较强,并不受饮食的影响。
Objective:To explore the inspection urine biochemical index to the treatment of primary osteoporosis evaluation value.Methods:retrospective analysis 70 patients with primary osteoporosis patients for clinical data,indicators PYD,DPD,Ca and urine HOP.Results:of the case group patients PYD/Cr,DPD/Cr,Ca/Cr,HOP/Cr significantly higher than normal group,P0.05.The case group therapy PYD/Cr,DPD/Cr is significantly lower before treatment,P0.05 Conclusion: PYD,DPD is a primary osteoporosis better diagnosis and treatment of the index,specificity is stronger,not under the influence of the diet.
出处
《中国医药导刊》
2012年第10期1817-1818,共2页
Chinese Journal of Medicinal Guide
关键词
尿生化指标
原发性骨质疏松
吡啶酚
脱氧吡啶酚
Urine biochemical index
Primary osteoporosis
Pyridine phenol
Deoxypyridinoline