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心肺复苏自主循环恢复后饲养方法对大鼠生存率的影响

Effect of Breeding Measure on the Survival Rate after Spontaneous Circulation Recovery of Cardiopulmonary Resuscitation in Rat
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摘要 目的:探讨不同饲养方法对大鼠心肺复苏模型制作中自主循环恢复后的生存率的影响。方法:将心肺复苏模型复苏成功后的大鼠随机分为对照组(n=16)和观察组(n=16),比较复苏后大鼠的饲养中引入新方法的观察组与普通饲养的对照组的48 h、72 h生存率和体重的变化。结果:观察组的死亡率低于对照组,但无统计学差异(P>0.05);观察组活到第7 d的大鼠体重下降幅度明显小于对照组(P<0.01)。结果:通过采用科学、合理、可行的饲养措施,可明显提高大鼠心肺复苏模型自主循环恢复后的生存率。 Objective: To study the effect of different breeding measure on the survival rate after spontaneous circulation recovery(ROSC) of cardiopulmonary resuscitation(CPR) in rat. Methods: The rats with ROSC of CPR were divided into control group (n=16) and observing group (n=16) by random. The rats were eared with various kinds of modified measures in observing group. The changes of body weight and survival rate in 48 h and 72 h after ROSC of CPR were compared between the two groups. Results: The mortality in the observing group was lower than that in the control group, but there was no significantly different(P〉0.05). The descent range of body weight in the observing group was obviously lower than that in the control group in rats which were survival in 7th days after ROSC of CPR(P〈0.01). Conclusions: The scientific, reasonable, feasible breeding measures could improve the survival rate of the rats after ROSC of CPR during model making.
出处 《岭南急诊医学杂志》 2012年第5期327-328,347,共3页 Lingnan Journal of Emergency Medicine
基金 广东省科技计划项目(2007B060401043003)
关键词 大鼠 心肺复苏模型 生存率 饲养方法 rat CPR model survival rate breeding measure
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参考文献6

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