丙泊酚对糖尿病患者手术中血糖和糖代谢激素的影响

目的:观察丙泊酚对糖尿病患者手术中及手术后血糖和糖代谢激素的影响。方法:ASAⅠ～Ⅱ级择期老年糖尿病眼科手术患者86例,随机分为两组,A组术中采用丙泊酚静脉麻醉,B组作为对照组,术中采用利多卡因局麻。分别于麻醉前、手术进行中30分钟、手术结束后1小时采血测定血糖和血浆胰岛素水平。结果:A组术后血糖和胰岛素与术前相比无显著性变化(P>0.05),B组术后血糖和胰岛素与术前相比显著性升高(P<0.05)。结论:静脉应用丙泊酚可明显抑制患者手术中的应激反应,减轻术中、术后糖代谢紊乱,促进患者术后恢复。

Objective：To investigate the effect of propofol on intraoperative blood sugar and hormones of glucose metabolism of diabetic patients.Method：100 patients undergoing selective ophthalmic surgery were randomly divided into a test group（ A group,n = 50） and a control group（ B group,n = 50）.Blood sugar and insulin were measured in 100 patients at three time points ：preinfusion,30min after the infusion and 1 hour after the end of infusion.Results：As compared with that at preinfusion,blood sugar and insulin were significantly decreased at B group（ P 0.05）.Conclusion：The intravenous infusion of propofol can suppress in the patient surgery the stress to respond obviously,reduce the sugar metabolism disorder,and promote the patient technique to restore.