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托吡酯治疗偏头痛对患者体重和静息代谢率影响的研究 被引量:5

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摘要 目的:在托吡酯治疗偏头痛过程中对患者体重和静息代谢率的影响进行全面评估。方法:选取18~70岁偏头痛患者,应用托吡酯100 mg.d-1进行连续4个月预防性治疗,在治疗前后对患者的体重、人体参数、皮褶厚度、体成分以及静息代谢率进行评估。结果:托吡酯治疗后体重平均减轻0.9 kg,体重指数(BMI)减少0.4 kg/m2,腰围和脂肪比例都明显下调,腹部皮褶厚度减少。但身体其他部位无明显差异,静息代谢率无明显影响。结论:托吡酯治疗偏头痛可使体重和BMI下降,主要表现为脂肪组织和腹部皮褶厚度的减少,与静息代谢率无关。
出处 《中国临床神经科学》 2012年第6期682-685,共4页 Chinese Journal of Clinical Neurosciences
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