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Sinularia sp.中化学成分的分离与结构鉴定

Isolation and Structural Identification of Chemical Constituents from Sinularia sp.
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摘要 利用硅胶色谱、凝胶色谱等分离方法从软珊瑚Sinularia sp.中分离得到6种化学成分.通过一维核磁共振波谱、二维核磁共振波谱和质谱等分析方法对化合物进行结构解析,确定为西松烷二萜类成分:lobocrassolide,lobo-hedleolide,(7Z)-lobohedleolide和2-epi-11Z-lobohedleolide;邻笨二甲酸酯类成分:1,2-benzenedicarboxylic acid di-isobutyl ester;甾醇类成分:ergosta-5-en-3β-ol.其中4种西松烷二萜类化合物为首次从该样品中获得. Six constituents were repeatedly isolated and purified from a soft coral Sinularia sp. by silica gel and Sephadex LH 20 chromatographies. On the basis of spectroscopic data of 1D NMR, 2D NMR and EI-MS, their chemical structures were identified as lobocrassolide, lobohedleolide, （TZ）-lobohedleolide, 2-epi-11Z-lobohedleolide, 1, 2-benzenedicarboxylic acid diisobutyl ester, ergosta-5-en-3β-ol. The compounds of cembranoid diterpenes are gained from this organism for the first time.
作者 吕芳 迟凯月 戴荣继 邓玉林
机构地区 北京理工大学生命学院
出处 《北京理工大学学报》 EI CAS CSCD 北大核心 2012年第10期1096-1100,共5页 Transactions of Beijing Institute of Technology
基金 国家教育部高等学校博士学科点专项科研基金资助项目(新教师课题基金资助项目 20091101120045)
关键词 软珊瑚 西松烷二萜 化学成分分离 结构鉴定 soft coral cembranoid diterpene constituent isolation structure identification
分类号 R931.7 [医药卫生—生药学]
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参考文献8

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二级参考文献42

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北京理工大学学报
2012年 第10期

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