静脉滴注硝酸异山梨酯治疗不稳定性心绞痛30例

Therapy with intravenous drip of isosorbide in 30 patients with unstable angina pectoris

目的 :观察 iv gtt硝酸异山梨酯 ( Iso)对不稳定性心绞痛 ( U AP)患者的疗效和安全性。方法 :30例不稳定性心绞痛患者 iv gtt Iso30～ 40 m g( 80～ 15 0 μg/m in) ,qd,疗程 10 d。对照组 iv gtt硝酸甘油治疗。结果 :30例中 15例症状完全缓解 ,12例发作次数减少 ,症状减轻 ,3例无效。结论 :iv gtt Iso对 U AP有效 。

AIM: To investigate the effects and safety of the therapy with intravenous drip of isosorbide in patients with unstable angina pectoris (UAP). METHODS: Thirty patients with UAP received intravenous drip of isosorbide (30-40 mg, 80-150 μg/min) once a day, and the course of therapy was 10 d. The patients in control group received intravenous drip of nitroglycerine. RESULTS: In 30 patients, the symptoms of 15 patients disappeared absolutely, the attack times of 12 patients decreased and the symptoms relieved, it was ineffective to 3 patients. CONCLUSION: Intravenous drip of isosorbide in patients with UAP is the significant effective therapy with few side effects, compared with nitroglycerine.