摘要
代谢组学是研究生物体内源性代谢物质的整体及其随内因和外因变化的科学分支,是系统生物学的一个重要组成部分。代谢组学是继基因组学、蛋白组学之后又一热点学科。本文着重介绍液相串联质谱和其统计分析软件在代谢组学中的应用,和目前临床生物标志物发现上取得的成果。
Metabonomics, one of the important branch in Systems Biology, mainly studied the whole biological enclogenous metabolites and the change of endogenous and exogenous factors. Metabonomics was another hot spot disciplines following genomics and proteomics. This paper focused on the application of liquid chromatography-tandem mass spectrometry and its statistical analysis software in metabonomics, and the achievements obtained in clinical biomarker.
出处
《分子诊断与治疗杂志》
2012年第6期425-427,共3页
Journal of Molecular Diagnostics and Therapy
关键词
代谢组学
液相色谱串联质谱
生物标志物
Metabonomics
Liquid chromatography-tandem mass spectrometry
Biomarker
