先天性小痣82例临床与病理分析

Clinical and pathological analysis of 82 cases of small congenital nevus

为了了解先天性小痣(SCN)的临床与病理特点 ,对 82例进行了分析。在临床上 ,SCN损害常为梭形或椭圆形褐黑色斑块 ,84%的损害大小超过 1cm ,表面粗糙不平 ,常覆盖有黑色粗毛 ;部位最常见于躯干和四肢。病理上 ,大部分病例黑素细胞巢局限于真皮网状层的上半部 ;2 /3的SCN可见到明显的交界活动性。由于先天性小痣比后天性痣易于恶变 ,故支持尽量在青春期前作预防性切除的意见。

In order to study the clinical and pathological characteristics, 82 cases of small congenital nevus(SCN) were reviewed Clinically, SCN was often spindle or oval shaped plaques, brown to black in colour in 84%of nevi the lesion size was over 1cm in greatest diameter Their surface was rough and usually covered with coarse black hairs Pathologically, in a great part of the cases, the nests of melanocytes were confined to the upper half of the reticular dermis, 2/3 of SCN showed marked junctional activity Because SCN is more liable to undergo malignant degeneration than acquired nevus (AN) , the best possible means is prophylactic excision before puberty