摘要
胚胎和成年哺乳动物脑内均存在神经干细胞。成纤维细胞生长因子 ( FGF)和表皮生长因子 ( EGF)对神经干细胞的增殖及分化有一定影响。 FGF和 EGF及其受体在胚胎期和成年期表达各异。 FGF和 EGF能促进神经干细胞增殖 ,在不同的条件下对分化的作用不同。
A certain number of neural stem cells exist in the embryonic and adult mammalian brain.Fibroblast growth factor(FGF)and epidermal growth factor(EGF)have some effects on the proliferation and differentiation of neural stem cells.The expression of FGF and EGF and their receptors vary in the embryonic and adult brain.FGF and EGF can promote the proliferation of nerual stem cells,and differentially influence their differentiation under different conditions. [
关键词
FGF
EGF
神经干细胞
细胞增殖
分化
fibroblast growth factor
epidermal growth factor
neural stem cell
