轻型头部外伤血清神经元特异性烯醇化酶与脑电图的对照研究

The contrast study of the neuron specific enolase with mild head injury and electroencephalogram

目的:探讨神经元特异性烯醇化酶(NSE)和脑电图(EEG)在轻型头部外伤中的变化。方法 :应用放射免疫法动态测定了血清NSE酶活性的变化 ,并进行EEG检查。结果 :患者组血清NSE酶活性较正常对照组明显升高(P<0.001)。患者EEG检查异常率56.3 %。结论 :NSE作为神经元损伤的敏感性标志物 ,脑电图所反映的脑机能状态的变化 ,对临床早期发现和治疗轻型头部外伤有重要的指导意义。

Objective:Study the change of the neuron specific enolase (NSE)and electroencephalogram(EEG)with mild head injury.Methods:Use radioimmunoassay to study the NSE and EEG.Results:The NSE of patient team increase obviously comparied with normal team(P< 0.001).The 40 EEG of 71 patients is abnormal,abnormal ratio is 56.3%. Conclusion :NSE and EEG has important use in find and treat mild head injury.