期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

缺血性卒中急性期血管内局部治疗技术的研究进展 被引量：1

下载PDF
导出
摘要 组织型纤溶酶原激活剂（tissueplasminogenacti．vator，t-PA）静脉溶栓是美国食品药品监督管理局（FDA）认证的缺血性卒中急性期唯一有效的治疗手段。但t－PA静脉溶栓时间窗较短（≤4．5h），对颈内动脉及大脑中动脉等大血管闭塞的溶栓效果较差，限制了其应用范围[1]。
作者 孙智善 刘毅 吉训明
机构地区 首都医科大学宣武医院北京老年病医疗研究中心 潍坊医学院神经外科
出处 《中国脑血管病杂志》 CAS 2012年第11期612-616,共5页 Chinese Journal of Cerebrovascular Diseases
基金 国家自然科学基金项目(81200915) 北京市科委重大项目(Z111107054311016)
关键词 卒中 脑缺血 血栓溶解疗法 血栓切除术 支架
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献36

  • 1Carpenter CR,Keim SM,Milne WK,et al. Thrombolytic therapy for acute ischemic stroke beyond three hours [ J ]. J Emerg Med,2011,40( 1 ) :82-92.
  • 2Bhatia R, Hill MD, Shobha N, et al. Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke: real-world experience and a call for action [J]. Stroke, 2010, 41 (10): 2254-2258.
  • 3Furlan A, Higashida R, Wechsler L, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism [ J ]. JAMA, 1999,282 ( 21 ) : 2003-2011.
  • 4Adams H, Adams R, Del Zoppo G, et al. Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update a scientific statement from the Stroke Council of the American Heart Association/American Stroke Association[ J]. Stroke,2005,36(4) :916-923.
  • 5Sorimachi T, Fujii Y, Tsuchiya N, et al. Recanalization by mechanical embolus disruption during intra-arterial thrombolysis in the carotid territory [ J ]. AJNR Am J Neurora diol,2004,25 ( 8 ) : 1391-1402.
  • 6Hitchcock KE, Holland CK. Ultrasound-assisted thrombolysis for stroke therapy: better thrombus break-up with bubbles[J]. Stroke,2010,41 ( 10 Suppl) :50-53.
  • 7Tomsick T, Broderick J, Carrozella J, et al. Revascularization results in the Interventional Management of Stroke II trial [ J]. AJNR Am J Neuroradio1,2008,29 ( 3 ) :582-587.
  • 8Berlis A, Lutsep H, Barnwell S, et al. Mechanical thrombolysis in acute ischemic stroke with endovascular photo acoustic recanalization [ J ]. Stroke, 2004, 35 ( 5 ) : 1112-1116.
  • 9Layton KF, White JB, Cloft H J, et al. Expanding the treatment window with meehanieal thrombeetomy in acute isehemie stroke [ J ]. Neuroradiology, 2006, 48 ( 6 ) : 402-404.
  • 10Liebig T, Reinartz J, Hannes R, et al. Comparative in vitro study of five mechanical embolectomy systems: effectiveness of clot removal and risk of distal embolization [ J ]. Neuroradiology ,2008,50 ( 1 ) :43-52.

同被引文献21

  • 1BANDERA E, BOTI'ERI M, MINELLI C, et al. Cerebralblood flow threshold of ischemic penumbra and infarct core in acute ischemic stroke : a systematic review [ J ]. Stroke, 2006, 37(5) : 1334 -1339.
  • 2KAUR H, PRAKASH A, MEDHI B. Drug therapy in stroke: from preclinical to clinical studies [ J ]. Pharmacology, 2013, 92(5/6) : 324 -334.
  • 3ASAHI M, WANG X, MORI T, et al. Effects of matrix metalloproteinase- 9 gene knock -out on the proteolysis of blood - brain barrier and white matter components after cerebral ischemia [ J ]. J Neurosci, 2001, 21 (19) : 7724 - 7732.
  • 4MOLINA C A. Reperfusion therapies for acute ischemic stroke: current pharmacological and mechanical approaches [ J ]. Stroke, 2011, 42(1 Suppl) : S16-S19.
  • 5FRANSEN P S, BEUMER D, BERKHEMER O A, et al. Mr CLEAN, a muhicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial [ J/OLJ. Trials, 2014, 15:34312015 - 12 - 15 ]. http://www, trialsjournal, corn/ content/15/1/343/. DOI : 10. 1186/1745 - 6215 - 15 - 343.
  • 6LEES K R, BLUHMKI E, VON KUMMER R, et al. Time to treatment with intravenous aheplase and outcome in stroke: an updated pooled analysis of ECASS, Atlantis, NINDS, and EPITHET trials[J]. Lancet, 2010, 375(9727): i695- 1703.
  • 7HACKE W. Interventional thrombectomy for major stroke - a step in the right direction [ J ]. N Engl J Med, 2015, 372 (1) : 76 -77.
  • 8HACKE W, DONNAN G, FIESCHI C, et al. Atlantis trials investigators ; ECASS trials investigators ; NINDS rt - PA study group investigators, association of outcome with early stroke treatment : pooled analysis of Atlantis, ECASS, and NINDS rt - PA stroke trials[J]. Lancet, 2004, 363(9411): 768 -774.
  • 9BERKHEMER O A, FRANSEN P S, BEUMER D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke[J]. N Engl J Med, 2015, 372(1) : 11 -20.
  • 10FURLAN A, HIGASHIDA R, WECHSLER L, et al. Intra- arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism [ J ]. JAMA, 1999, 282 (21) : 2003 - 2011.

引证文献1

二级引证文献6

中国脑血管病杂志
2012年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部